Prezados, boa tarde! Venho aqui pedir indicação de artigos científicos confiáveis, de revistas reco

Advance Rheumatology - saiu recentemente o Consenso de Fibromialgia da Sociedade Brasileira de Reumatologia. Atualização fresquinha.

Sim, há comprovação científica robusta de que o treino de resistência (musculação) melhora a função cognitiva, e evidências emergentes sugerem que os exercícios de membros inferiores podem ter um papel particularmente relevante nesse benefício, embora a relação não seja exclusiva dos membros inferiores. Uma revisão publicada no JAMA Internal Medicine confirmou que as doenças autoimunes afetam 5–10% da população dos EUA, com marcante predominância feminina, e que as respostas imunes inatas e adaptativas são mais fortes em mulheres do que em homens. A musculação, e particularmente os exercícios de membros inferiores, pela grande massa muscular envolvida e consequente maior liberação de miocinas neuroprotetoras — tem comprovação científica para melhorar a função cognitiva, inclusive em pacientes com fibromialgia. E a predominância feminina de ~80% nas doenças autoimunes é um dado confirmado, explicado por fatores genéticos (cromossomo X), hormonais (estrogênio), epigenéticos e evolutivos. 1. Comparative Efficacy of Exercise Interventions for Cognitive Health in Older Adults: A Network Meta-Analysis. Experimental Gerontology. 2025. Zhang J, Ye W, Li W, Zhang F, Wu Z.New 2. Acute Effects of Resistance Exercise on Cognitive Function in Healthy Adults: A Systematic Review With Multilevel Meta-Analysis. Sports Medicine. 2019. Wilke J, Giesche F, Klier K, et al. 3. Effects of Resistance Exercise on Cognitive Function, Neurotrophic Factors, Brain Structure, and Brain Function in Older Adults: A Narrative Review. Journal of Alzheimer's Disease : JAD. 2025. Jiang W, Wang X, Mao L.New 4. Working Memory Improvements Following Supramaximal High-Intensity Interval Training Predicted by Increased Prefrontal Cortex Activation and Leg Strength Gains. Cerebral Cortex. 2025. Sandström S, Simonsson E, Hedlund M, Rosendahl E, Boraxbekk CJ.New 5. Physical Activity and Muscle-Brain Crosstalk. Nature Reviews. Endocrinology. 2019. Pedersen BK. 6. Roles of Myokines in Exercise-Induced Improvement of Neuropsychiatric Function. Pflugers Archiv : European Journal of Physiology. 2019. Kim S, Choi JY, Moon S, et al. 7. Neuroprotective Mechanisms of Exercise and the Importance of Fitness for Healthy Brain Ageing. Lancet. 2025. Tari AR, Walker TL, Huuha AM, Sando SB, Wisloff U. 8. Investigating the Mediating Effect of Myokines on Exercise-Induced Cognitive Changes in Older Adults: A Living Systematic Review and Meta-Analysis. Neuroscience and Biobehavioral Reviews. 2025. Vints WAJ, Gökçe E, Langeard A, et al.New 9. Exercise Intensity-Dependent Effects of Arm and Leg-Cycling on Cognitive Performance. PloS One. 2019. Hill M, Walsh S, Talbot C, Price M, Duncan M. 10. Impact of Being Physically Active on the Brain Electrocortical Activity, Brain Volumetry and Performance in the Stroop Color and Word Test in Women With Fibromyalgia. Scientific Reports. 2022. Villafaina S, Leon-Llamas JL, Murillo-Garcia A, Gusi N. 11. Efficacy of Nonpharmacological Interventions for Individual Features of Fibromyalgia: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Pain. 2022. Kundakci B, Kaur J, Goh SL, et al. 12. Effects of Resistance Training on the Mental Health of Patients With Fibromyalgia: A Systematic Review. Clinical Rheumatology. 2021. Vilarino GT, Andreato LV, de Souza LC, Branco JHL, Andrade A. 13. Fibromyalgia: Diagnosis and Management. American Family Physician. 2023. Winslow BT, Vandal C, Dang L.Guideline 14. Out of Balance: The Role of Evolutionary Mismatches in the Sex Disparity in Autoimmune Disease. Medical Hypotheses. 2021. Keestra SM, Male V, Salali GD. 15. Autoimmune Disease in Women: Endocrine Transition and Risk Across the Lifespan. Frontiers in Endocrinology. 2018. Desai MK, Brinton RD. 16. Clinical Advances in Sex- and Gender-Informed Medicine to Improve the Health of All: A Review. JAMA Internal Medicine. 2020. Bartz D, Chitnis T, Kaiser UB, et al. 17. Incidence, Prevalence, and Co-Occurrence of Autoimmune Disorders Over Time and by Age, Sex, and Socioeconomic Status: A Population-Based Cohort Study of 22 Million Individuals in the UK. Lancet. 2023. Conrad N, Misra S, Verbakel JY, et al. 18. Female Predisposition to TLR7-driven Autoimmunity: Gene Dosage and the Escape From X Chromosome Inactivation. Seminars in Immunopathology. 2019. Souyris M, Mejía JE, Chaumeil J, Guéry JC. 19. The Dynamic Epigenetic Regulation of the Inactive X Chromosome in Healthy Human B Cells Is Dysregulated in Lupus Patients. Proceedings of the National Academy of Sciences of the United States of America. 2021. Pyfrom S, Paneru B, Knox JJ, et al. 20. Altered X-Chromosome Inactivation Predisposes to Autoimmunity. Science Advances. 2024. Huret C, Ferrayé L, David A, et al. 21. Environmental Toxins and Toxic Metals in Autoimmune Diseases: Sex Differences, Hormonal Influences, and Immune Dysregulation. Autoimmunity Reviews. 2025. Bjørklund G, Wallace DR, Kangarlou K, Hossain F, Peana M.New 22. Mechanisms Underlying Sex Differences in Autoimmunity. The Journal of Clinical Investigation. 2024. Fairweather D, Beetler DJ, McCabe EJ, Lieberman SM.